hrp0082p2-d1-318 | Diabetes | ESPE2014

Serum Level of Osteoprotegerin and Total sRANKL in Adolescents with Type 1 Diabetes Mellitus

Szalecki Mieczyslaw , Wierzbicka Elzbieta , Pludowski Pawel , Jaworski Maciej

Background: There is still small clinical data regarding the influence of IDDM on bone structure, density and biochemical markers of bone turnover.Objective and hypotheses: To evaluate the potential role of OPG/sRANKL system in adolescents with IDDM and the influence of age, sex, metabolic control, diabetes duration and age of onset.Method: Serum concentration of OPG and total sRANKL in 60 children (25 boys and 33 girls) with IDDM ...